playing house!

April 5, 2009 at 9:05 pm (med, school)

Ethan! u want to join me for 20-30 min jogging tomorrow?

oh but u said u hate joggin… sry

hahaa sat mornings are my foootball days! interested?

oh no, im terrible at football

alternative pathway of complement activation is this part of innate or adaptive. its innate right?

complements are part of innate immunity. i think.

haha ok. still working on cutting down the damned thing

yeah me too. nearly done. i have in my notes that the alternative pathway is activated by gram- bacteria. our staph is gram +

do u have any notes on septicaemia?

did u include pathophysiology of shock?

haha yeah

i don’t even haf any idea why its included..

i’m working on shock now and i think septicaemia caused the shock…but i dont have any notes on septicaemia

where did the case say she was in shock?

she collapsed during the night b/c of the adrenal crisis. collapsed there means shock i think. no sry she collapsed because she had septic shock

don’t think so. An adrenal crisis would have caused her levels of Cortisol and Aldosterone to fall dramatically. The consequences of this would be a reduced blood glucose concentration, reduced circulating volume, and reduced blood pressure. This seems to have lead to Elaine going into shock (insufficient blood perfusion to the body), due to her falling BP and decreased circulating volume. She may have also become hypoglycaemic, leading to weakness – this would have contributed.

i c. and the adrenal crisis was caused by the infection?

yeah! likely

Thanks mate! Thats why its better if you work with others. So septicaemia is irrelevant?

yeah. i did abit of research on this one. that’s how i came with the above conclusion. what do u think makes sense right? most logical deduction directly linked to adrenal crisis

makes perfect sense!

as opposed to

• I think Elaine has Critical Illness Related Corticosteroid Insufficiency Syndrome (CIRCI). This is a condition of adrenal crisis without the adrenal part. Cytokines involved in the inflammatory response, especially TNF-α and IL-1, suppress the Hypothalamic-Pituitary-Adrenal Axis and prevents the release of Cortisol. TNF-α inhibits the release of ACTH. Furthermore, these cytokines increase tissue Cortisol resistance by down-regulating production of the glucocorticoid receptor. So not only is circulating levels of Cortisol low, the tissues are less responsive to it, compounding the problem. The reasoning for this immunoendocrinological process is because of Cortisol’s immunosuppressive effects, suppressing it allows for a greater inflammatory response.


that’s bullshit. i checked it half an hr ago. this guy’s over-researched.

hahha. yeah probably

i will use his shock paragraph though.

considering what we’ve been taught in endocrinology it’s likely that my reason is the answer since we nvr learnt before about the disease that guy came up with lol

he is trying to play House MD. he is a very smart guy but this time he got it wrong- big time

hahaha. i don’t know. i guess he just missed the simpler link but if you think about it that disease does also make sense assuming its correct. after all it does explain it as well, no?

it does but so do a million others. its a weird, fancy illness that fits into the puzzle. so does harry potter vanishing her adrenal glands – that makes sense. (or not)


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s

%d bloggers like this: